Inverse FoldDir: Structure-conditioned Protein Sequence Design by Dirichlet Flow Matching
Alp Tartici, M. Stojkovic, An-Ru Tian, Michael C. Jewett, R. Altman, Bruce Wittmann
September 2026
National Library of Medicine | September 2026
Bruce Wittmann
Senior Applied Scientist
Publications
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FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications
Kieran Didi, Sarah Alamdari, Alex Lu, Bruce Wittmann, Kadina E. Johnston, Ava P. Amini, Ali Madani, Maya Czeneszew, Christian Dallago, Kevin Kaichuang Yang
ICML 2026 | May 2026
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Strengthening nucleic acid biosecurity screening against generative protein design tools
Bruce Wittmann, Tessa Alexanian, Craig Bartling, Jacob Beal, Adam Clore, James Diggans, Kevin Flyangolts, Bryan Gemler, Tom Mitchell, Steven T. Murphy, Nicole E. Wheeler, Eric Horvitz
October 2025
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Steering Generative Models with Experimental Data for Protein Fitness Optimization
Jason Yang, Wenda Chu, Daniel Khalil, Raul Astudillo, Bruce Wittmann, Frances H. Arnold, Yisong Yue
NeurIPS 2025 | May 2025
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Toward AI-Resilient Screening of Nucleic Acid Synthesis Orders: Process, Results, and Recommendations
Bruce Wittmann, Tessa Alexanian, Craig Bartling, Jacob Beal, Adam Clore, James Diggans, Kevin Flyangolts, Bryan T. Gemler, Tom Mitchell, Steven T. Murphy, Nicole E. Wheeler, Eric Horvitz
December 2024
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Inverse FoldDir: Structure-conditioned Protein Sequence Design by Dirichlet Flow Matching
Alp Tartici, M. Stojkovic, An-Ru Tian, Michael C. Jewett, R. Altman, Bruce Wittmann
September 2026
National Library of Medicine | September 2026
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FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications
Kieran Didi, Sarah Alamdari, Alex Lu, Bruce Wittmann, Kadina E. Johnston, Ava P. Amini, Ali Madani, Maya Czeneszew, Christian Dallago, Kevin Kaichuang Yang
ICML 2026 | May 2026
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Strengthening nucleic acid biosecurity screening against generative protein design tools
Bruce Wittmann, Tessa Alexanian, Craig Bartling, Jacob Beal, Adam Clore, James Diggans, Kevin Flyangolts, Bryan Gemler, Tom Mitchell, Steven T. Murphy, Nicole E. Wheeler, Eric Horvitz
October 2025
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Steering Generative Models with Experimental Data for Protein Fitness Optimization
Jason Yang, Wenda Chu, Daniel Khalil, Raul Astudillo, Bruce Wittmann, Frances H. Arnold, Yisong Yue
NeurIPS 2025 | May 2025
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Toward AI-Resilient Screening of Nucleic Acid Synthesis Orders: Process, Results, and Recommendations
Bruce Wittmann, Tessa Alexanian, Craig Bartling, Jacob Beal, Adam Clore, James Diggans, Kevin Flyangolts, Bryan T. Gemler, Tom Mitchell, Steven T. Murphy, Nicole E. Wheeler, Eric Horvitz
December 2024
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Inverse FoldDir: Structure-conditioned Protein Sequence Design by Dirichlet Flow Matching
Alp Tartici, M. Stojkovic, An-Ru Tian, Michael C. Jewett, R. Altman, Bruce Wittmann
September 2026
National Library of Medicine | September 2026
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Inverse FoldDir: Structure-conditioned Protein Sequence Design by Dirichlet Flow Matching
Alp Tartici, M. Stojkovic, An-Ru Tian, Michael C. Jewett, R. Altman, Bruce Wittmann
September 2026
National Library of Medicine | September 2026
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FLIP2: Expanding Protein Fitness Landscape Benchmarks for Real-World Machine Learning Applications
Kieran Didi, Sarah Alamdari, Alex Lu, Bruce Wittmann, Kadina E. Johnston, Ava P. Amini, Ali Madani, Maya Czeneszew, Christian Dallago, Kevin Kaichuang Yang
ICML 2026 | May 2026
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Steering Generative Models with Experimental Data for Protein Fitness Optimization
Jason Yang, Wenda Chu, Daniel Khalil, Raul Astudillo, Bruce Wittmann, Frances H. Arnold, Yisong Yue
NeurIPS 2025 | May 2025
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Strengthening nucleic acid biosecurity screening against generative protein design tools
Bruce Wittmann, Tessa Alexanian, Craig Bartling, Jacob Beal, Adam Clore, James Diggans, Kevin Flyangolts, Bryan Gemler, Tom Mitchell, Steven T. Murphy, Nicole E. Wheeler, Eric Horvitz
October 2025
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Toward AI-Resilient Screening of Nucleic Acid Synthesis Orders: Process, Results, and Recommendations
Bruce Wittmann, Tessa Alexanian, Craig Bartling, Jacob Beal, Adam Clore, James Diggans, Kevin Flyangolts, Bryan T. Gemler, Tom Mitchell, Steven T. Murphy, Nicole E. Wheeler, Eric Horvitz
December 2024
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