{"id":725929,"date":"2021-02-11T17:00:20","date_gmt":"2021-02-12T01:00:20","guid":{"rendered":"https:\/\/cm-edgetun.pages.dev\/en-us\/research\/?post_type=msr-research-item&#038;p=725929"},"modified":"2021-02-11T17:00:20","modified_gmt":"2021-02-12T01:00:20","slug":"a-large-scale-database-of-t-cell-receptor-beta-tcr%ce%b2-sequences-and-binding-associations-from-natural-and-synthetic-exposure-to-sars-cov-2","status":"publish","type":"msr-research-item","link":"https:\/\/cm-edgetun.pages.dev\/en-us\/research\/publication\/a-large-scale-database-of-t-cell-receptor-beta-tcr%ce%b2-sequences-and-binding-associations-from-natural-and-synthetic-exposure-to-sars-cov-2\/","title":{"rendered":"A large-scale database of T-cell receptor beta (TCR\u03b2) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2"},"content":{"rendered":"<p>We describe the establishment and current content of the ImmuneCODE\u2122 database, which includes hundreds of millions of T-cell Receptor (TCR) sequences from over 1,400 subjects exposed to or infected with the SARS-CoV-2 virus, as well as over 135,000 high-confidence SARS-CoV-2-specific TCRs. This database is made freely available, and the data contained in it can be downloaded and analyzed online or offline to assist with the global efforts to understand the immune response to the SARS-CoV-2 virus and develop new interventions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>We describe the establishment and current content of the ImmuneCODE\u2122 database, which includes hundreds of millions of T-cell Receptor (TCR) sequences from over 1,400 subjects exposed to or infected with the SARS-CoV-2 virus, as well as over 135,000 high-confidence SARS-CoV-2-specific TCRs. This database is made freely available, and the data contained in it can be [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"msr-url-field":"","msr-podcast-episode":"","msrModifiedDate":"","msrModifiedDateEnabled":false,"ep_exclude_from_search":false,"_classifai_error":"","msr-author-ordering":null,"msr_publishername":"","msr_publisher_other":"","msr_booktitle":"","msr_chapter":"","msr_edition":"","msr_editors":"","msr_how_published":"Research 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The highlighted research here suggested answers to questions such as how the SARS-CoV-2 may have evolved from animals to humans, how to improve the potency of peptide vaccines, examining the role of T-cells in immunity, using T-cell receptor sequencing to predict disease severity, and simulating the mechanism by&hellip;","_links":{"self":[{"href":"https:\/\/cm-edgetun.pages.dev\/en-us\/research\/wp-json\/wp\/v2\/msr-project\/921738"}]}},{"ID":552123,"post_title":"Microsoft Immunomics","post_name":"immunomics","post_type":"msr-project","post_date":"2018-11-21 10:18:41","post_modified":"2025-04-30 14:15:39","post_status":"publish","permalink":"https:\/\/cm-edgetun.pages.dev\/en-us\/research\/project\/immunomics\/","post_excerpt":"The human immune system is an astonishing diagnostic system, continuously adapting itself to detect any signal of disease in the body. Essentially, the state of the immune system tells a story about virtually everything affecting a person\u2019s health. 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