{"id":696577,"date":"2020-10-07T10:57:42","date_gmt":"2020-10-07T17:57:42","guid":{"rendered":"https:\/\/cm-edgetun.pages.dev\/en-us\/research\/?post_type=msr-research-item&#038;p=696577"},"modified":"2020-10-07T18:05:29","modified_gmt":"2020-10-08T01:05:29","slug":"maternal-smoking-before-and-during-pregnancy-and-the-risk-of-sudden-unexpected-infant-death","status":"publish","type":"msr-research-item","link":"https:\/\/cm-edgetun.pages.dev\/en-us\/research\/publication\/maternal-smoking-before-and-during-pregnancy-and-the-risk-of-sudden-unexpected-infant-death\/","title":{"rendered":"Maternal smoking before and during pregnancy and the risk of sudden unexpected infant death"},"content":{"rendered":"<div id=\"sec-2\" class=\"subsection\">\n<p id=\"p-4\"><strong>OBJECTIVES:<\/strong>\u00a0Maternal smoking during pregnancy is an established risk factor for sudden unexpected infant death (SUID). Here, we aim to investigate the effects of maternal prepregnancy smoking, reduction during pregnancy, and smoking during pregnancy on SUID rates.<\/p>\n<\/div>\n<div id=\"sec-3\" class=\"subsection\">\n<p id=\"p-5\"><strong>METHODS:<\/strong>\u00a0We analyzed the Centers for Disease Control and Prevention Birth Cohort Linked Birth\/Infant Death Data Set (2007\u20132011: 20\u2009685\u2009463 births and 19\u2009127 SUIDs). SUID was defined as deaths at <1 year of age with\u00a0<em>International Classification of Diseases, 10th Revision<\/em>\u00a0codes R95 (sudden infant death syndrome), R99 (ill-defined or unknown cause), or W75 (accidental suffocation or strangulation in bed).<\/p>\n<\/div>\n<div id=\"sec-4\" class=\"subsection\">\n<p id=\"p-6\"><strong>RESULTS:<\/strong>\u00a0SUID risk more than doubled (adjusted odds ratio [aOR] = 2.44; 95% confidence interval [CI] 2.31\u20132.57) with any maternal smoking during pregnancy and increased twofold between no smoking and smoking 1 cigarette daily throughout pregnancy. For 1 to 20 cigarettes per day, the probability of SUID increased linearly, with each additional cigarette smoked per day increasing the odds by 0.07 from 1 to 20 cigarettes; beyond 20 cigarettes, the relationship plateaued. Mothers who quit or reduced their smoking decreased their odds compared with those who continued smoking (reduced: aOR = 0.88, 95% CI 0.79\u20130.98; quit: aOR = 0.77, 95% CI 0.67\u20130.87). If we assume causality, 22% of SUIDs in the United States can be directly attributed to maternal smoking during pregnancy.<\/p>\n<\/div>\n<div id=\"sec-5\" class=\"subsection\">\n<p id=\"p-7\"><strong>CONCLUSIONS:<\/strong>\u00a0These data support the need for smoking cessation before pregnancy. If no women smoked in pregnancy, SUID rates in the United States could be reduced substantially.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>OBJECTIVES:\u00a0Maternal smoking during pregnancy is an established risk factor for sudden unexpected infant death (SUID). Here, we aim to investigate the effects of maternal prepregnancy smoking, reduction during pregnancy, and smoking during pregnancy on SUID rates. METHODS:\u00a0We analyzed the Centers for Disease Control and Prevention Birth Cohort Linked Birth\/Infant Death Data Set (2007\u20132011: 20\u2009685\u2009463 births [&hellip;]<\/p>\n","protected":false},"featured_media":0,"template":"","meta":{"msr-url-field":"","msr-podcast-episode":"","msrModifiedDate":"","msrModifiedDateEnabled":false,"ep_exclude_from_search":false,"_classifai_error":"","msr-author-ordering":null,"msr_publishername":"","msr_publisher_other":"","msr_booktitle":"","msr_chapter":"","msr_edition":"","msr_editors":"","msr_how_published":"","msr_isbn":"","msr_issue":"4","msr_journal":"Pediatrics","msr_number":"","msr_organization":"","msr_pages_string":"","msr_page_range_start":"","msr_page_range_end":"","msr_series":"","msr_volume":"143","msr_copyright":"Copyright \u00a9 2019 by the American Academy of Pediatrics","msr_conference_name":"","msr_doi":"","msr_arxiv_id":"","msr_s2_paper_id":"","msr_mag_id":"","msr_pubmed_id":"","msr_other_authors":"","msr_other_contributors":"","msr_speaker":"","msr_award":"","msr_affiliation":"","msr_institution":"","msr_host":"","msr_version":"","msr_duration":"","msr_original_fields_of_study":"","msr_release_tracker_id":"","msr_s2_match_type":"","msr_citation_count_updated":"","msr_published_date":"2019-4-4","msr_highlight_text":"","msr_notes":"","msr_longbiography":"","msr_publicationurl":"","msr_external_url":"","msr_secondary_video_url":"","msr_conference_url":"","msr_journal_url":"","msr_s2_pdf_url":"","msr_year":0,"msr_citation_count":0,"msr_influential_citations":0,"msr_reference_count":0,"msr_s2_match_confidence":0,"msr_microsoftintellectualproperty":true,"msr_s2_open_access":false,"msr_s2_author_ids":[],"msr_pub_ids":[],"msr_hide_image_in_river":0,"footnotes":""},"msr-research-highlight":[],"research-area":[13553],"msr-publication-type":[193715],"msr-publisher":[],"msr-focus-area":[],"msr-locale":[268875],"msr-post-option":[],"msr-field-of-study":[],"msr-conference":[],"msr-journal":[],"msr-impact-theme":[],"msr-pillar":[],"class_list":["post-696577","msr-research-item","type-msr-research-item","status-publish","hentry","msr-research-area-medical-health-genomics","msr-locale-en_us"],"msr_publishername":"","msr_edition":"","msr_affiliation":"","msr_published_date":"2019-4-4","msr_host":"","msr_duration":"","msr_version":"","msr_speaker":"","msr_other_contributors":"","msr_booktitle":"","msr_pages_string":"","msr_chapter":"","msr_isbn":"","msr_journal":"Pediatrics","msr_volume":"143","msr_number":"","msr_editors":"","msr_series":"","msr_issue":"4","msr_organization":"","msr_how_published":"","msr_notes":"","msr_highlight_text":"","msr_release_tracker_id":"","msr_original_fields_of_study":"","msr_download_urls":"","msr_external_url":"","msr_secondary_video_url":"","msr_longbiography":"","msr_microsoftintellectualproperty":1,"msr_main_download":"","msr_publicationurl":"","msr_doi":"","msr_publication_uploader":[{"type":"doi","viewUrl":"false","id":"false","title":"https:\/\/doi.org\/10.1542\/peds.2018-3325","label_id":"243109","label":0},{"type":"url","viewUrl":"false","id":"false","title":"https:\/\/pediatrics.aappublications.org\/content\/pediatrics\/143\/4\/e20183325.full-text.pdf","label_id":"243132","label":0}],"msr_related_uploader":"","msr_citation_count":0,"msr_citation_count_updated":"","msr_s2_paper_id":"","msr_influential_citations":0,"msr_reference_count":0,"msr_arxiv_id":"","msr_s2_author_ids":[],"msr_s2_open_access":false,"msr_s2_pdf_url":null,"msr_attachments":[],"msr-author-ordering":[{"type":"text","value":"Tatiana M. 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