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Medical, health, & genomics

Accelerating discoveries in medicine, health, and genomics through advances in computing, AI, and data science.

Tyger - portable MRI story: comparison of MRI scans

When MRI images come into focus: How Tyger scales image reconstruction signals

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The AI Revolution in Medicine, Revisited [Podcast]

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Talos: Scaling rare disease diagnosis with automated, iterative genomic reanalysis

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Microsoft Research Forum is a virtual series showcasing research with real-world impact, from fundamental exploration to responsible AI, scaling innovation through products and open source, and supporting positive change in society. By participating in Microsoft…

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Publication

Consequences of training data composition for deep learning models in single-cell biology

Ajay Nadig, Akshaya Thoutam, Madeline Hughes, Anay Gupta, Andrew W. Navia, Nicolo Fusi, Srivatsan Raghavan, Peter S. Winter, Ava P. Amini, Lorin Crawford

bioRxiv | February 2025

Project

Microsoft Research Blog

Exploring the structural changes driving protein function with BioEmu-1

February 20, 2025 | Sarah Lewis, Tim Hempel, Jose Jimenez-Luna, Michael Gastegger, Yu Xie, Victor García Satorras, Osama Abdin, Bas Veeling, Ryota Tomioka, Frank Noé

Meet BioEmu-1 from Microsoft Research. This deep learning model can generate thousands of protein structures per hour, unlocking new possibilities for protein scientists and drug discovery and research.

The image shows eight different 3D models of protein structures. Each model is color-coded with various segments in blue, green, orange, and other colors to highlight different parts of the protein.

Publication

Toward Accurate pH-Dependent Binding Constant Predictions Using Molecular Docking and Constant-pH MD Calculations.

M. Yousef, Nuno F B Oliveira, João N. M. Vitorino, Pedro BPS Reis, Piotr Drączkowski, M. Maj, K. Jóźwiak, M. Machuqueiro

Journal of chemical theory and computation | February 2025

Publication

Addressing biomedical data challenges and opportunities to inform a large-scale data lifecycle for enhanced data sharing, interoperability, analysis, and collaboration across stakeholders

Vivek Sriram, Ashley Conard, Ilyana Rosenberg, Dokyoon Kim, Scott Saponas, Amanda K. Hall

Scientific Reports | February 2025, Vol 15

Publication

Leveraging public data: Changes in local economic distress and drug overdose deaths at the county level, 2000 – 2019

Shaddy K. Saba, Juan M. Lavista Ferres, Bill Weeks

International Journal of Public Health | February 2025

Project

Publication

Boosting GPT Models for Genomics Analysis: Generating Trusted Genetic Variant Annotations and Interpretations through RAG and fine-tuning

Shuangjia Lu, Erdal Cosgun

Bioinformatics Advances | February 2025

Medical, health, & genomics

When MRI images come into focus: How Tyger scales image reconstruction signals

The AI Revolution in Medicine, Revisited [Podcast]

Talos: Scaling rare disease diagnosis with automated, iterative genomic reanalysis

Microsoft Health Futures

Microsoft Research Forum

Consequences of training data composition for deep learning models in single-cell biology

Exploring the structural changes driving protein function with BioEmu-1

Toward Accurate pH-Dependent Binding Constant Predictions Using Molecular Docking and Constant-pH MD Calculations.

Addressing biomedical data challenges and opportunities to inform a large-scale data lifecycle for enhanced data sharing, interoperability, analysis, and collaboration across stakeholders

Leveraging public data: Changes in local economic distress and drug overdose deaths at the county level, 2000 – 2019

National AI Research Resource (NAIRR) Pilot

Beyond Hospital Walls: Transforming Healthcare with In-Home Monitoring

AI in the Era of GPT: Transforming the Future of Work and Discovery

Boosting GPT Models for Genomics Analysis: Generating Trusted Genetic Variant Annotations and Interpretations through RAG and fine-tuning

Medical, health, & genomics

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