illustration of DNA strand and abstract shapes on a computer screen on a green gradient background

Medical, health, and genomics

Digital pathology helps decode tumor microenvironments for precision immunotherapy. GigaPath is a novel vision transformer that can scale to gigapixel whole-slide images by adapting dilated attention for digital pathology. In joint work with Providence and UW, we’re sharing Prov-GigaPath, the first whole-slide pathology foundation model pretrained on large-scale real-world data, for advancing clinical research and discovery.

GigaPath: Whole-Slide Foundation Model for Digital Pathology

Research Forum Ep2 | Panel | Transforming the Natural Sciences with AI

Research Forum 2 | Panel Discussion: Transforming the Natural Sciences with AI

white icons of first aid kit, DNA strand, laptop monitor with overlapping eye, and microscope on a blue and green gradient background

Scaling early detection of esophageal cancer with AI

female doctor / nurse reviewing a tablet

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Published Date

Publication

Automated Deep Segmentation of Healthy Organs in PSMA PET/CT Images

Ivan Klyuzhin, Guillaume Chausse, Ingrid Bloise, Juan M. Lavista Ferres, Carlos Uribe, Arman Rahmim

Journal of Nuclear Medicine | May 2021

Project

Publication

Impact of Human Leukocyte Antigen-Associated Polymorphisms on Variability of HIV-1 Accessory and Regulatory Proteins.

Doreen Kamori, Zafrul Hasan, Jonathan M. Carlson, A I Kawana-Tachikawa, Hiroyuki Gatanaga, Shinichi Oka, Takamasa Ueno

AIDS Research and Human Retroviruses | April 2021, Vol 37(12): pp. 962-966

Project

Publication

Risk of rapid evolutionary escape from biomedical interventions targeting SARS-CoV-2 spike protein.

Debra Van Egeren, Alexander Novokhodko, Madison Stoddard, Uyen Tran, Bruce Zetter, Michael Rogers, Bradley L. Pentelute, Jonathan M. Carlson, Mark Hixon, Diane Joseph-McCarthy, Arijit Chakravarty

PLOS ONE | April 2021, Vol 16(4): pp. e0250780

Project Project

Event

Dedicated to inspiring and championing health innovation, the Lake Nona Impact Forum is a three-day, invitation-only event that takes place in Lake Nona in Orlando, FL, a 17-square-mile Living Laboratory dedicated to health, wellbeing enabled…

Publication

Redefining replication in multi-ancestry genome-wide association studies

Smith Sp, Shahamatdar S, Cheng W, Zhang S, Paik J, Graff M, Haiman C, Matise T, North Ke, Peters U, Kenny E, Gignoux C, Wojcik G, Lorin Crawford, Ramachandran S

bioRxiv | April 2021

Tool

Bing Coronavirus Query Set

Dataset containing Aggregated and anonymized queries from across the world with Coronavirus intent. This dataset was curated from the Bing search logs (desktop users only) over the period of Jan 1st, 2020 – (Current Month…

GitHub Publication

Tool

InnerEye-DICOM-RT

InnerEye-DICOM-RT contains tools to convert medical datasets in NIFTI format to DICOM-RT. Datasets converted using this tool can be consumed directly by InnerEye-DeepLearning. Most of the work is done by a .NET Core 2.1 project…

GitHub Publication

Publication

A systematic approach to inserting split inteins for Boolean logic gate engineering and basal activity reduction.

Trevor Y. H. Ho, Alexander Shao, Zeyu Lu, Harri Savilahti, Filippo Menolascina, Lei Wang, Neil Dalchau, Baojun Wang

Nature Communications | April 2021, Vol 12(1): pp. 2200-2200

Project

Publication

Algorithmic copywriting: automated generation of health-related advertisements to improve their performance

Brit Youngmann, Elad Yom-Tov, Ran Gilad-Bachrach, Danny Karmon

Information Retrieval Journal | April 2021

Project

Publication

The tumor microenvironment drives transcriptional phenotypes and their plasticity in metastatic pancreatic cancer

Srivatsan Raghavan, Peter S. Winter, Andrew W. Navia, Hannah L. Williams, Alan DenAdel, Radha L. Kalekar, Jennyfer Galvez-Reyes, Kristen E. Lowder, Nolawit Mulugeta, Manisha S. Raghavan, Ashir A. Borah, Kevin S. Kapner, Sara A. Väyrynen, Andressa Dias Costa, Raymond W.S. Ng, Junning Wang, Emma Reilly, Dorisanne Y. Ragon, Lauren K. Brais, Alex M. Jaeger, Liam F. Spurr, Yvonne Y. Li, Andrew D. Cherniack, Isaac Wakiro, Asaf Rotem, Bruce E. Johnson, James M. McFarland, Ewa T. Sicinska, Tyler E. Jacks, Thomas E. Clancy, Kimberly Perez, Douglas A. Rubinson, Kimmie Ng, James M. Cleary, Lorin Crawford, Scott R. Manalis, Jonathan A. Nowak, Brian M. Wolpin, William C. Hahn, Andrew J. Aguirre, Alex K. Shalek

bioRxiv | April 2021

Medical, health, and genomics

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